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Alfonso d'Este, Duke of Ferrara, Duke of Modena, Duke of Reggio, was born 21 July 1476 in Subiaco, Italy to Ercole I d'Este (1431-1505) and Eleanor of Naples (1450-1493) and died 31 October 1534 Ferrara, Italy of unspecified causes. He married Anna Sforza (1476-1497) January 1491 JL . He married Lucrezia Borgia (1480-1519) 1502 JL in Ferrara, Italy.
Children
| Name | Birth | Death | Joined with |
| Alessandro d'Este (1497-1514) | |||
| Name | Birth | Death | Joined with |
| Ercole II d'Este (1508-1559) | 5 April 1508 | 3 October 1559 Ferrara | Renée of Orleans (1510-1574) |
| Ippolito II d'Este (1509-1572) | |||
| Alessandro d'Este (1514-1516) | |||
| Leonora d'Este (1515-1575) | |||
| Francesco d'Este (1516-1578) | |||
| Isabella Maria d'Este (1519-1519) | |||
| Name | Birth | Death | Joined with |
| Alfonso d'Este (1527-1587) | 10 March 1527 Ferrara, Italy | 1 November 1587 Ferrara, Italy | Giulia Feltria della Rovere (1531-1563) Violante Signa (1546-1609) |
Footnotes (including sources)
| ‡ General |
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