Andrew Newcomb was born 1680 in Eastham, Barnstable County, Massachusetts, United States to Simon Newcomb (1665-1745) and Deborah Lathrop (1664-1756) and died 9 December 1748 Truro, Barnstable County, Massachusetts, United States of unspecified causes. He married Mercy Oldham (1689-1730) 4 November 1708 in Scituate, Plymouth County, Massachusetts, United States.
Children
| Name | Birth | Death | Joined with |
| Mercy Newcomb (1710-) | |||
| Joshua Newcomb (1712-1751) | |||
| Jesse Newcomb (1718-1801) | |||
| Abigail Newcomb (1720-1821) | |||
| Robert Newcomb (1722-1802) | |||
| Lemuel Newcomb (1724-1787) | |||
Siblings
| Name | Birth | Death | Joined with |
| Andrew Newcomb (1680-1748) | 1680 Eastham, Barnstable County, Massachusetts, United States | 9 December 1748 Truro, Barnstable County, Massachusetts, United States | Mercy Oldham (1689-1730) |
| Rebecca Newcomb (c1685-) | |||
| John Deacon Newcomb (1688-1765) | |||
| Thomas Newcomb (c1691-c1761) | |||
| Hezekiah Newcomb (1693-1772) | |||
| Obadiah Newcomb (c1695-1761) | 1695 Edgartown, Dukes County, Massachusetts, United States | 4 May 1761 Hebron, Tolland County, Connecticut, United States | Abigail Curtis (c1693-1757) |
| Deborah Newcomb (1696-1756) | |||
| Benjamin Newcomb (1700-1774) | |||
| Elizabeth Newcomb (1702-1727) | |||
| Joanna Newcomb | |||
| Simon Newcomb (c1705-c1770) | |||