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Ann Cooper Tilley was born 7 November 1585 in Henlow, Bedfordshire, England to Edmund Cooper (1542-1619) and Mary Wyne (1543-1598) and died January 1621 Plymouth Colony, Plymouth, Plymouth County, Massachusetts of unspecified causes. She married Edward Tilley (c1588-1621) 20 June 1614 in Henlow, Bedfordshire, England.


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