Comfort Bigelow Brigham was born 23 September 1707 in Malden, Massachusetts to John Bigelow (1675-1769) and Jerusha Garfield (1677-1758) and died 24 September 1755 Marlborough, Middlesex County, Massachusetts of unspecified causes. She married Joseph Brigham (1706-1786) 26 August 1728 in Marlborough, Middlesex County, Massachusetts.
Children
| Name | Birth | Death | Joined with |
| Mehitabel Brigham (1725-1749) | |||
| Sarah Brigham (1731-) | |||
| Lavina Brigham (1733-1784) | |||
| Joseph Brigham (1735-1742) | |||
| Comfort Brigham (1737-1742) | |||
| Martha Brigham (1739-1769) | 9 September 1739 Marlborough, Middlesex County, Massachusetts | 22 May 1769 Marlborough, Middlesex County, Massachusetts | Daniel Barnes (1736-1813) |
| Stephen Brigham (1741-1764) | |||
| Comfort Brigham (1745-1771) | |||
| Joseph Brigham (1747-1810) | |||
| Jonah Brigham (1747-1827) | |||
| Lucy Brigham (1752-) | |||
Siblings