Constantin Cantemir was born 1705 to Antioh Cantemir (1670-1724) and Caterina Ceaur (c1675-1708) and died 6 October 1776 Rogan, Kharkiv Rayon, Kharkiv Oblast, Ukraine of unspecified causes. He married Irina Balș (c1710-1737) 1733 . He married Natalya Ivanovna Golovina (c1720-c1745) 1741 . He married Sofia Bogdanovna Passek (1722-1783) .
Children
| Name | Birth | Death | Joined with |
| Maria Cantemir (c1735-1787) | 1705 | 1735 | Pantazi Câmpineanu (c1725-1764) |
| Name | Birth | Death | Joined with |
| Dmitri Konstantinovich Kantemir (1749-1820) | 1749 | 17 May 1820 Kiev, Ukraine | Cecilia Mustafa (c1755-c1810) Elizaveta Khrushova (c1760-c1830) |
Siblings
| Name | Birth | Death | Joined with |
| Ana Cantemir (c1697-1767) | 1697 | 1767 | Radu Brâncoveanu (1690-1714) Toader Paladi (c1695-1755) |
| Ioniță Cantemir (c1698-1754) | 1698 | May 1754 Iași, Iași County, Romania | Marghiolița Caradja (c1705-c1740) Catrina NN |
| Dimitrie Cantemir (1700-1759) | 28 April 1700 Constantinople, Turkey | 1758 Moscow, Russia | |
| Maria Cantemir (c1703-c1755) | 1703 | 1755 | Constantin Dudescu (c1695-1767) |
| Constantin Cantemir (1705-1776) | 1705 | 6 October 1776 Rogan, Kharkiv Rayon, Kharkiv Oblast, Ukraine | Irina Balș (c1710-1737) Natalya Ivanovna Golovina (c1720-c1745) Sofia Bogdanovna Passek (1722-1783) |