Col Daniel Appleton was born 16 March 1751 in Haverhill, Essex County, Massachusetts to Samuel Appleton (1713-1780) and Mary Russell (1716-1803) and died 15 May 1828 Haverhill, Essex County, Massachusetts of unspecified causes. He married Lydia Ela (1747-1826) 26 October 1775 in Haverhill, Essex County, Massachusetts.
Children
| Name | Birth | Death | Joined with |
| William Appleton (1776-) | |||
| Alice Appleton (1778-1842) | |||
| Abigail Appleton (1780-1853) | |||
| Samuel Appleton (1783-1787) | |||
| Daniel Appleton (1785–1849) | 10 December 1785 Haverhill, Essex County, Massachusetts, United States | 27 March 1849 New York City, New York, United States | Hannah Adams (1791-1859) |
| Lydia Appleton (1787-1863) | |||
Siblings
| Name | Birth | Death | Joined with |
| Samuel Appleton (1740-1784) | |||
| Thomas Appleton (1743-1803) | |||
| Mary Appleton (1746-1830) | |||
| Hannah Appleton (1748-1750) | |||
| Daniel Appleton (1751-1828) | 16 March 1751 Haverhill, Essex County, Massachusetts | 15 May 1828 Haverhill, Essex County, Massachusetts | Lydia Ela (1747-1826) |
| William Appleton (1754-1798) | |||
| Hannah Appleton (1756-1824) | |||