Ebenezer Lewis was born 20 December 1666 in Barnstable, Barnstable County, Massachusetts to Edward Lewis (1640-1703) and Hannah Cobb (1639-1729) and died 9 January 1759 Barnstable, Barnstable County, Massachusetts of unspecified causes. He married Anna Lathrop (1673-1715) 1 April 1691 in Barnstable, Barnstable County, Massachusetts.
Children
| Name | Birth | Death | Joined with |
| Sarah Lewis (c1691-1737) | 1691 | 21 March 1737 | Ebenezer Hinckley (1685-1751) |
| Susannah Lewis (1694-1753) | |||
| Lothrop Lewis (1702-1773) | |||
| George Lewis (1704-1757) | |||
| Nathaniel Lewis (1707-1751) | |||
| John Lewis (1709-) | |||
| David Lewis (1711-) | 8 November 1711 Barnstable, Barnstable County, Massachusetts | Abiah Flagg (1715-) | |
Siblings