Edmund Knowles was born 6 March 1686 in Quarlton, England, United Kingdom and died 18 January 1762 Princess Anne, Maryland, United States of unspecified causes.
Children
| Name | Birth | Death | Joined with |
| Richard Knowles (1717-1791) | 16 August 1717 Princess Anne, Maryland, United States | 15 September 1791 Seaford, Delaware, United States | Elizabeth Prettyman (1722-1765) |
Siblings