Edward Brantley was born 1714 in Southampton County, Virginia, United States of America to James Brantley (1695-1742) and Ruth Unknown and died 21 June 1765 Halifax County, North Carolina, United States of America of unspecified causes. He married Martha Unknown (c1710-) .
Children
| Name | Birth | Death | Joined with |
| Robert Brantley (1740-1795) | 1740 Halifax County, North Carolina, United States of America | 1795 Halifax County, North Carolina, United States of America | Sarah Rorie (c1732-) |
| Lewis Brantley (1740-1799) | |||
| William Brantley (1742-1806) | |||
| Edward Brantley (1744-) | |||
| Benjamin Brantley (1750-) | |||
| Anne Brantley (1758-) | |||
Siblings
| Name | Birth | Death | Joined with |
| Edward Brantley (1714-1765) | 1714 Southampton County, Virginia, United States of America | 21 June 1765 Halifax County, North Carolina, United States of America | Martha Unknown (c1710-) |
| John Brantley (1725-1785) | |||
| William Brantley (1726-1826) | |||
| Brittain Brantley (1730-) | |||