Elizabeth Holbrook Sprague was born circa 1645 in England to William Holbrook (1620-1699) and Elizabeth Pitts (1625-1696) and died 5 July 1699 Weymouth, Norfolk County, Massachusetts of unspecified causes. She married John Sprague (1638-1683) 13 December 1666 in Hingham, Plymouth County, Massachusetts.
Research Notes
Her birthday must be closer to 1644 instead of 1624.
Children
| Name | Birth | Death | Joined with |
| John Sprague (1669-1669) | |||
| Elizabeth Sprague (1674-1731) | 1674 Rehoboth, Bristol County, Massachusetts | 10 July 1731 Rehoboth, Bristol County, Massachusetts | Benjamin Wilson (1670-1750) |
| John Sprague (1676-) | |||
| Millicent Sprague (1678-) | |||
| William Sprague (1679-1752) | |||
| Persis Sprague (1681-) | |||
| Ebenezer Sprague (1682-1731) | |||
Siblings
| Name | Birth | Death | Joined with |
| Elizabeth Holbrook (1624-1699) | 1645 England | 5 July 1699 Weymouth, Norfolk County, Massachusetts | John Sprague (1638-1683) |
| Jane Holbrook (1644-1702) | |||
| Mehitable Holbrook (1645-1719) | |||
| Hopestill Holbrook (1647-1706) | |||
| William Holbrook (1654-) | |||
| John Holbrook (1660-1735) | |||
| Experience Holbrook (1670-) | |||