Esther Cloyes Howe was born 27 April 1702 in Framingham, Middlesex County, Massachusetts to James Cloyes (1768-1725) and Mary Towne (1681-1717) and died 27 July 1759 Shrewsbury, Worcester County, Massachusetts of unspecified causes. She married Daniel Howe (1681-1768) 17 June 1725 in Shrewsbury, Worcester County, Massachusetts.
Children
| Name | Birth | Death | Joined with |
| Daniel Howe (1728-) | |||
| Nathan Howe (1728-) | |||
| Jotham Howe (1728-1809) | 28 October 1728 Shrewsbury, Worcester County, Massachusetts | February 1809 Barre, Worcester County, Massachusetts | Priscilla Rice (1731-1819) |
| Gideon Howe (1731-1815) | |||
| William Howe (1733-1791) | |||
| Lucy Howe (1736-1802) | |||
| Mary Howe (1738-1817) | |||
Siblings