Abbott family
- Simon Abbott (-)
- Dorcas Abbott (-)
Adams family
- Francis Adams (-)
- John Adams (-)
- Charles Adams (-)
Alford family
- Moses Alford (-c1708)
- Aaron Alford (living in 1738-)
- Moses Alford, (-c1733)
Alley family
- John Alley (living in 1730-)
- John Alley (living in 1756-)
Ambrose family
- Abraham Ambrose (-c1738)
- Abraham Ambrose, Jr. (-c1758)
- Thomas Ambrose (1700/01-c1740)
- John Ambrose (1710-), planter
- John Ambrose, Jr. (bap1727--)
Andrews family
- Samuel Andrews (living in 1727-), schoolmaster
- Christopher Andrews (-c1677)
- John Andrews (living in 1760-)
- Martha Andrews (-), named in her daughter's will on 19 Sep 1743
Bowie family
- John Bowie, Sr (1688-1759), land owner
- Gov. Oden Bowie (1828-1894), 34th Governor of Maryland, Maryland State Senator
- Gov. Robert Bowie (1750-1818), Governor of Maryland, Member of the Maryland House of Delegates
- Hon. Thomas Fielder Bowie (1808-1869), Member of the U.S. House of Representatives from Maryland's 6th district, Member of the Maryland House of Delegates
- Hon. Walter Bowie (1748-1810), Member of the Maryland House of Delegates, Maryland State Senator
- Capt. Hon. William Bowie (1721-), Member of the Assembly of Freeman, delegate to the Annapolis Convention of (1774-1776)
- Hon. William Duckett Bowie (1803-1873), Member of the Maryland House of Delegates, member of the Levy Court of Prince George's County
Brice family
- John Brice, Jr. (1705-1766)
- Hon. John Brice III (1738-1820), Mayor of Annapolis, lawyer, businessman and political leader
- Gov. James Brice (1746-1801), Governor of Maryland, Mayor of Annapolis, Maryland
Carroll family
- Hon. Charles Carroll the Settler (1661-1720), Attorney General of the Maryland Colony
- Charles Carroll II of Annapolis (1702-1782)
- Hon. Charles Carroll (1723-1783) (barrister)
- Hon. Charles Carroll of Carrollton (1737-1832), United States Senator form Maryland
- Hon. Daniel Carroll (1730-1796), Member of the U.S. House of Representatives from Maryland's 6th district
- The Most Reverend John Carroll, SJ (1735-1815), Archbishop of Baltimore
- Hon. John Lee Carroll (1830-1911), 37th Governor of Maryland, Maryland State Senate
- Col. Henry James Carroll (-)
- Thomas King Carroll (1793-1873), 21st Governor of Maryland
- Anna Ella Carroll (1815-1894), politician
- Hon. James Carroll (1791-1873), Judge of the orphan's court and a trustee of the poor, Director of the Baltimore & Ohio Railroad and the Chesapeake & Ohio Canal Company
- Brevet Maj. Gen. Samuel Sprigg "Red" Carroll ( 1832-1893), Commander of the 8th Ohio Infantry, fought in the Battle of Gettysburg
Baltimore
Dorsey family
- Edward Dorsey (c.1615-1659), he was the immigrant from England and died on Kent Island as a boat wright. In 1658 he converted to Quakerism and downed off of Kent Island in 1659.
- Col. Edward Dorsey (c.1644-1705), Esq., in 1667 he was a boat wright like his father; in 1679, 1686 and in 1689 he was Justice of Anne Arundel County; in 1686 he was Captain of militia 1687 he was Major of Horse of Anne Arundel County; on 4 Sep 1689 he was Major of Anne Arundel County; on 9 Oct 1664 he was commissioned Associate Commissioner in Chancery; on 17 Oct 1694, in 1695, 1696 and 1697 he was Burges of Anne Arundel County; in 1701-1705 he was Associate Commissioner for Baltimore; on 2 Mar 1695/96 he was Judge of High. Court of Chancery; in 1702 he was commissioned Colonel; in 1694 he was on the Committee to lay out the town lots and a common for Annapolis; in 1696 he was Trustee of King William and Mary School and a Commissioner for the erection of St. Anne's Church in Annapolis. About 28 Feb 1694/95 the first session of Mary Legislature, which was in Annapolis was held at his house when he was a Major in Annapolis.
- Hon. John Dorsey (1650-1715)
- Edward Dorsey (1678-1701)
- Joshua Dorsey (1686-1747),
- Capt. Hon. John Dorsey (1699-1761); on 10 Jun 1734 he and his brother John panted 632 acres under the name of Brother's Partnership; in 1712/14 he was Justice of Baltimore County; in 1742 he was Captain of Militia
- Ruth Dorsey (1710-1789), she was born in Annapolis and then died in Anne Arundel.
Southern Maryland
Brent family
- Margaret Brent (c1601-c1671)
- Mary Brent (-)
- Giles Brent (-)
- Fulke Brent (-)
Anne Arundel County
Todd family
- John Phelps Todd (1672-1733)
- John Todd (1715-1775)
- Betsy Todd (1738-1776)
Calvert County
Brooke family
- Gov. Robert Brooke, Sr. (1602-1655), Governor of Maryland for three months
- Maj. Thomas Brooke, Sr. (1632-1676), Member of the House of Burgess, High Sheriff and Chief Justice
- Col. Thomas Brook, Jr. (1659-c1630), 2 degree Governor of Restored Proprietary Government
Calvert family
- Benedict Leonard Calvert (1700-1732), 15th Proprietary Governor of Maryland
- Benedict Swingate Calvert (1722-1788), 3rd Proprietary Governor of Maryland
- Henry Harford (1758-1835), 5th Proprietary Governor of Maryland
Chaplin family
- William Chaplin (1625-1669), planter, juror, proprietor of three hundred acres of land on Hooper's Island; his father was Capt. Isaac Chaplin of the British Royal Navy and arrived in Virginia in 1608.
- William Chaplin, Jr. (1659-1718), inherited his father's plantation, juror
- Mary Chaplin (1663-)
- Isaac Chaplin (-1743)
- Solomon Chaplin (-1765)
- Thomas Chaplin (-1730)
- Mary Chaplin (-)
- Elizabeth Chaplin (-)
Eastern Shore
Dorchester County
Hooper family
- Capt. Henry Hooper I (c1600-1649), immigrant, Captain of the Calvert County Militia, Gentlemen Justice of the Peace for Calvert County, a first settler of Hooper's Island
- Elizabeth Hooper (c1622-1646)
- Mary Hooper (bet1625/1633-bet1663/1665)
- Alice Hooper (c1630-1703)
- Richard Hooper (1640-1673)
- Henry Hooper, Jr. (-1676)
Travers family
- William Travers I c1642-1700), immigrant from Ireland, Justice of the Calvert County Court and the Dorchester County Court
- William Travers (1684-1730)
- Mary Travers (1710-1777)
Somerset County
Bozman family
- John Bozman (1650-1716), arrived in Somerset County, Maryland from Accomack County, VA
- George Bozman (1682-1760)
- Ann Bozman (1705-1748)
Connor family
- John Connor (1660-1718)
- Elijah Connor (1720-)
Cullen family
- George Cullen (1650-1683)
- John Cullen (1674-1718)
Daugherty family
- Nathaniel Daugherty (c1630-1703)
- Nathaniel Daugherty (1650-1687)
- John Daugherty (c1683-1757)
- Isaac Daugherty (c1733-c1762)
- Rachel Daugherty (1762-)
Dennis family
- Donogh "Donnock" Dennish, Esq. (c1638-1716/17), High Sheriff of Somerset County, Maryland in 1685; Constable of Annemessex, Somerset County, Maryland in 1683
Horsey family
- Hon. Stephen Horsey (1620-1671), he was born on the Isle of Wight, England and immigrated to Northampton, Virginia and then came to Somerset County, Maryland; he was one of the main founders of Somerset County, Maryland
- Col. Isaac Horsey (1665-1752)
- Sarah Horsey (1689-1723)
Lankford family
- John Lankford (1652-1720)
- Joseph Lankford (1680-1758)
- Benjamin Lankford (1708-1788)
- Isabel Lankford (c1735-1788)
Lawson family
- Rev. Robert Lawson (c1665-bef1713)
- Samuel Lawson (c1680-bef1756)
- Hance Lawson (1700-aft1746)
- Samuel Lawson (c1723-aft1788)
London family
- Maj. Hon. Ambrose London (c1618-1706, immigrant, planter, Justice of the Peace, elected to the Lower House of Maryland General Assembly
- Mary London (1644-1730)
- Thomas London (1647-1662/63)
Ruth London (1657-)
- Abigail London (1660-1692)
Martin family
- Francis Martin (c1658-1699), he panted 150 acres of land
- Mathew Martin (1684-1684)
- Mary Martin (1687-1748)
- Sarah Martin (1689-)
- Frances Martin (1691-), he was proprietor of 345 acres and owner of "Parker's Place"
- John Martin (1693-)
- Martha Martin (1695-)
Riggin family
- Teague Riggin I (c1640-1707), immigrant and proprietor of 1,000 acres in Maryland. His father was Tiegh O'Dowda Reagh (c.1610-1645), who's parents were Prince Donal MacCarthy Reagh (1572-1612) and Lady Elena MacCarthy, daughter of Cormac Og MacCarthy, 1st Vicount of Muskerry, 17th Lord of Muskerry (1570-1640) and Lady Margaretha O'Brien (1575-1626), daughter of Donough O'Brien, 4th Earl of Thomond (-1624) and Elean Roche (1550-1583)
- Mary Riggin (1667/68-)
- Teague Riggin III (1670-1721/22)
- Ambrose Riggin (1673-)
- Sarah Riggin (1676-c1743)
- Ruth Riggin (1677/78-)
- John Riggin (c1680-), planter
- Darby Riggin (1683-), planter
- Rachel Riggin (1686-)
- Samuel Riggin (1689-)
Schoolfield family
- George Schoolfield (1741-1798)
- Isaac Bozeman Schoolfield (1775-1847)
Taylor family
- Hope Taylor (c1664-1696), emigrated from Accomack County, Virginia to Somerset County, Maryland. He was the sone of William Taylor II (c.1638-1697) and Elizabeth Hope (c.1640-); William Taylor II was the son of William Taylor I who was the owner of 2,500 acres in Virginia.
- Elizabeth Taylor (1684-1720)
Ward family
- Cornelius Ward I (c1639-1722/23), immigrant, a first settler of Somerset County, Maryland, proprietor of 1,375 acres, and owner of Bear Point, Cork, Long Acres and White Oak Swamp, Justice of the Peace
- John Ward (1667/68-aft1736)
- Alice Ward (1665-1687)
- Cornelius Ward, Jr. (1670-1736)
- William Ward (1672/73-1716)
- Thomas Ward (1672-aft1717)
- Margaret Ward (1678-aft1772)
- Samuel Ward (1684-1761)
- Stephen Ward (af1686-1736)
- Jonathan Ward (aft1686-aft1736)
- Catherine Ward (aft1686-aft1722)
- Josephen Ward (1688-1765)
- Samuel Ward (1684-1761)
- Martha Ward (c1730-1761)
Wilson family
- Abraham Wilson (1761-1801)
- Abraham Wilson, Jr. (1801-bef1850)
- Elijah Thomas Wilson (1818-bef1860)
- Capt. John Moses Ewing Wilson (1851-1900)
Annemessex
Dickerson family
- Edward Dickerson (1627-1682), Gent., immigrant
- Elizabeth Dickerson (1644-1733)
- John Dickerson (1662-)
- Peter Dickerson (1664-1733)
- Edward Dickerson, Jr. (1666-)
- Mary Dickerson (1673-)
Sommers family
- Benjamin Sommers (c.1635-1715), he immigrated from Yorkshire or Hertfordshire, England first settling in Northampton, Virginia and panted 300 acres of land which he named "Emmessex." On 23 Sep 1683 he panted 200 more acres of land which he named "Musketa Hummock," which were both located in what is now Crisfield, Maryland. He further panted another 100 acres of land which he named it "Little Worth." He panted in total 550 acres which would become know as Somers Cove before it became Crisfield. Somers Cove quickly became a seafood town and has been ever since. The ancestral home of the family was in Yorkshire and Hertfordshire, England where the name was spelled Somers.
- John Summers (c.1682-1760)
- Deborah Summers (c.1725-aft.1800)
Sterling family
- John Sterling I (1641-1705)
- John Sterling, Jr. (1676-1741)
- John Sterling III (1700-1779)
- Travers Sterling (1740-1836)
Roach family
- John Roach I (1635-1718), immigrant, proprietor of 757 acres
- John Roach, Jr. (1663-1727)
- Sarah Roach (1666-1709)
- Mary Roach (1669-1709)
- Elizabeth Roach (1670-)
- Abigail Roach (1673-)
- William Roach (1675-1687)
- Arabella Roach (1679-)
- Nathaniel Roach (1681-1721)
- Michael Roach (1683-1720)
- Hannah Roach (1687-)
- Joseph Roach (1689-)
- Samuel Roach (1692-1736)
Kent Island
Moore family
- Richard Moore (1625-1676), immigrant from Ireland and settled on Kent, Island
- John Moore (c1660-1717)
- Thomas Moore (c1678-1721)
- Isaac Moore I (c1707-1771)
- Isaac Moore II (c1736-aft1810)
Morumsco
Minshall family
- Jeffrey Minshall I (1620-1675), immigrant, owner of 400 acres called "Adventures" at the head of Marumsco Creek
- Ann Minshall (c1666-)
Smith Island
Tyler family
- John Tyler, Jr. (1686-1734/35), Henry Smith sold 200 acres of land to him and he was one of the two people that bought land from Henry Smith. John and another person were the first two settlers in Smith Island, Somerset County, Maryland.
- Richard Tyler (1692-aft.1733
- John Tyler (1693-1693/94)
- John Tyler (1694-bef.1778)
- Aldon Tyler (c.1701-)
- Else Tyler (c.1702-aft.1733)
- Thomas Tyler (c1708-1812)
- Thomas Tyler (c1718-1812)
- Butler Tyler (c.1732-1823)
- Thomas Tyler (c.1734-1812)
- John Tyler (c.1736-)
- Jemima Tyler (c.1737-)
- Mary Tyler (c1738-)
- Jacob Tyler (c.1743-1808)
- Littleton Tyler (1751-)
- Arabella Tyler (1755-1836)
- David Tyler (1756-1823)