Frances Wood Howe was born 10 May 1645 in Sudbury, Middlesex County, Massachusetts to John Wood (1609-1678) and Mary Parmenter (1610-1690) and died 14 May 1718 Marlborough, Middlesex County, Massachusetts of unspecified causes. She married Isaac Howe (1648-1724) 17 June 1671 in Marlborough, Middlesex County, Massachusetts.
Children
| Name | Birth | Death | Joined with |
| Elizabeth Howe (1673-1750) | |||
| Sarah Howe (1675-1733) | 28 January 1675 Sudbury, Middlesex County, Massachusetts | 4 December 1733 Marlborough, Middlesex County, Massachusetts | Moses Newton (1669-1736) |
| Mary Howe (1677-1751) | |||
| John Howe (1680-1680) | |||
| John Howe (1682-1754) | |||
| Bethia Howe (1684-1751) | |||
| Hannah Howe (1688-1773) | |||
| Thankful Howe (1691-1741) | |||
Siblings
| Name | Birth | Death | Joined with |
| Mary Wood (1634-1707) | 10 June 1634 Sudbury, Suffolk, England | 16 September 1707 Marlborough, Middlesex County, Massachusetts | John Bellows (1622-1682) |
| Samuel Wood (1636-1718) | |||
| Abigail Wood (1636-1719) | |||
| Dorcas Wood (1637-1692) | |||
| Hannah Wood (1638-1666) | |||
| John Woods (1641-1716) | 8 May 1641 Sudbury, Middlesex County, Massachusetts | 5 April 1716 Marlborough, Middlesex County, Massachusetts | Lydia Rice (1649-1723) |
| Katherine Wood (1646-1727) | |||
| Frances Woods (1645-1718) | 10 May 1645 Sudbury, Middlesex County, Massachusetts | 14 May 1718 Marlborough, Middlesex County, Massachusetts | Isaac Howe (1648-1724) |
| James Wood (1647-1718) | |||
| Isaac Wood (1655-1740) | |||