Hannah Holbrook Pierce was born 13 January 1643 in Weymouth, Norfolk County, Massachusetts to John Holbrook (1618-1699) and Elizabeth Stream (1624-1688) and died after September 1721 Swansea, Bristol County, Massachusetts of unspecified causes. She married Ephraim Pierce (1650-1719) 1670 in Weymouth, Massachusetts, United States.
Children
| Name | Birth | Death | Joined with |
| Ezrikam Pierce (1671-1749) | |||
| Ephraim Pierce (1674-1768) | October 1674 Warwick, Rhode Island, United States | 18 October 1768 Gloucester, Rhode Island, United States | Mary Low (1671-bef1769) |
| Michael Pierce (1676-) | |||
| Elizabeth Pierce (1678-1679) | |||
| Rachel Pierce (1678-1718) | |||
| Hannah Pierce (1680-1736) | |||
| Experience Pierce (1682-1722) | |||
| John Pierce (1684-1722) | |||
| Benjamin Pierce (1686-1698) | |||
Siblings