Harmonius Alkire was born 8 March 1730 in Moorefield, West Virginia, United States to Harmonas I. Alkire (1700-1796) and Mary Craymore (1708-1796) and died 7 July 1800 Paris, Kentucky, United States of unspecified causes.
Children
| Name | Birth | Death | Joined with |
| John D Alkire (1764-1836) | 16 August 1764 Romney, West Virginia, United States | 1 October 1836 Greenview, West Virginia, United States | Susannah Nation Neff (1768-1832) |
Siblings
| Name | Birth | Death | Joined with |
| Harmonius Alkire (1730-1800) | 8 March 1730 Moorefield, West Virginia, United States | 7 July 1800 Paris, Kentucky, United States | Lydia Patton (1739-1800) |