Henry Pelham Pelham-Clinton, 5th Duke of Newcastle-under-Lyne, 12th Earl of Lincoln, was born 22 May 1811 in Westminster, Greater London, England, United Kingdom to Henry Pelham Pelham-Clinton, 4th Duke of Newcastle (1785-1851) and Georgina Elizabeth Mundy (1789-1822) and died 18 October 1864 of unspecified causes. He married Susan Harriet Catherine Hamilton (1814-1889) 27 November 1832 in Hamilton Palace, Hamilton, South Lanarkshire, Scotland, United Kingdom.
|Henry Pelham Alexander Pelham-Clinton, 6th Duke of Newcastle (1834-1879)|
|Edward William Pelham-Clinton (1836-1907)|
|Susan Charlotte Catherine Pelham-Clinton (1839-1875)||7 April 1839 London, Greater London, England, United Kingdom||6 September 1875||Adolphus Frederick Charles William Vane-Tempest (1825-1864)|
|Arthur Pelham-Clinton (1840-1870)|
|Albert Sidney Pelham-Clinton (1845-1884)|