Hope Huckins Nelson was born 10 March 1677 in Barnstable, Barnstable County, Massachusetts to John Huckins (1649-1678) and Hope Chipman (1652-1728) and died 7 December 1782 Barnstable, Barnstable County, Massachusetts of unspecified causes. She married Thomas Nelson (1675-1755) 24 March 1697 in Barnstable, Barnstable County, Massachusetts.
Children
| Name | Birth | Death | Joined with |
| Hannah Nelson (1699-1761) | 10 April 1699 Middleborough, Plymouth County, Massachusetts | Jabez Wood (1691-1772) | |
| Hope Nelson (1700-) | |||
| John Nelson (1702-1732) | |||
| Lois Nelson (1704-) | |||
| Ruth Nelson (1705-) | |||
| Elizabeth Nelson (1708-1748) | |||
| Thomas Nelson (1710-) | |||
| Sarah Nelson (1712-1782) | |||
| William Nelson (1714-1776) | |||
| Foxel Nelson (1716-) | |||
| Amos Nelson (1718-) | |||
| Ebenezer Nelson (1721-) | |||
Siblings
| Name | Birth | Death | Joined with |
| Elizabeth Huckins (1671-1741) | October 1671 Barnstable, Barnstable County, Massachusetts | 12 July 1741 Barnstable, Barnstable County, Massachusetts | John Lewis (1666-1738) |
| Mary Huckins (1673-1743) | |||
| Experience Huckins (1675-1733) | |||
| Hope Huckins (1677-1782) | 10 March 1677 Barnstable, Barnstable County, Massachusetts | 7 December 1782 Barnstable, Barnstable County, Massachusetts | Thomas Nelson (1675-1755) |