Isaac Balica was born circa 1572 to Melentie Balica (c1542-1586) and Șcheuca Movilă (c1545-c1600) and died circa 9 August 1612 of unspecified causes.
Isaac Balica was great vistier (1607-1611), hatman (1609) and pârcălab (1609). He died after he was wounded in the Battle of Cornul lui Sas (1612)
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