Isaac Gore was born 27 September 1782 in Shenandoah County, Virginia, United States to John Gore (1761-1834) and Elizabeth Grigsby (c1760-1838) and died circa 1848 Overton County, Tennessee, United States of unspecified causes. He married Elizabeth (Nettie) Simcoe (c1782-) .
|Offspring of Isaac Gore and Elizabeth (Nettie) Simcoe (c1782-)|
|Mounce Gore (c1810-c1849)||1792 Overton, Tennessee, United States||1849 Windle, Overton County, Tennessee, United States||Millie Gore (c1805-aft1879) Millie Gore (c1805-aft1879) Rebecca Simcock (1815-1867)|
- Vice President Albert Arnold Gore Jr. (1948-) - 3x Great Grandson