Gen. Isaac Maltby was born 10 November 1767 in Northford, New Haven County, Connecticut, United States to Benjamin Maltby (1717-1796) and Elizabeth Fowler (1728-1810) and died 9 September 1819 Waterloo, Seneca County, New York, United States of unspecified causes. He married Lucinda Murray (1771-1844) 10 November 1790 .
Children
| Name | Birth | Death | Joined with |
| Seth Murray Maltby (1791-1873) | |||
| Elizabeth White Maltby (1794-1886) | |||
| Benjamin Maltby (1796-) | |||
| Maria Maltby (1799-1864) | 15 March 1799 Massachusetts, United States | 29 September 1864 Buffalo, Erie County, New York, United States | Thomas Cutting Love (1789-1853) |
| Aurelia Maltby (1801-1898) | |||
| Julia Ann Maltby (1805-) | |||
| Isaac Fowler Maltby (1807-1846) | |||
| Lucinda Maltby (1810-) | |||
| Martha Church Maltby (1815-1889) | |||
Siblings
| Name | Birth | Death | Joined with |
| Elihu Maltby (1753-1753) | |||
| Benjamin Maltby (1755-1823) | |||
| Thaddeus Maltby (1757-1776) | |||
| Jonathan Maltby (1759-1856) | |||
| Elizabeth Malby (1761-1781) | |||
| Sarah Maltby (1763-1848) | |||
| Isaac Maltby (1767-1819) | 10 November 1767 Northford, New Haven County, Connecticut, United States | 9 September 1819 Waterloo, Seneca County, New York, United States | Lucinda Murray (1771-1844) |
| Stephen Maltby (1769-1812) | |||