Isaac Stafford was born 2 September 1763 in Foster, Providence County, Rhode Island, United States to John Stafford (1735-?) and Mary King (1733-) and died 19 January 1831 Preston, Chenango County, New York, United States of unspecified causes.
Children
| Name | Birth | Death | Joined with |
| John Stafford (1792-1855) | 13 May 1792 Guilford, Windham County, Vermont, United States | 1855 | Sophia Randall (?-?) |