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Isabella de Aviz de Portugal was born 24 October 1503 in Lisbon, Portugal to Manuel I of Portugal (1469-1521) and Maria of Aragon (1482-1517) and died 1 May 1539 Toledo, Spain of unspecified causes. She married Charles V of the Holy Roman Empire (1500-1558) 10 March 1526 JL in Seville, Spain. Alfred the Great (849-899)/s, Charlemagne (747-814)/s, Henry II of England (1133-1189)/s, Hugh Capet (c940-996)/s, William I of England (1027-1087)/s, Rollo of Normandy (860-932)/s.
Children
| Offspring of Isabella de Portugal and Charles V of the Holy Roman Empire (1500-1558) | |||
| Name | Birth | Death | Joined with |
| Philip II of Spain (1527-1598) | 21 May 1527 Valladolid, Spain | 13 September 1598 El Escorial, Spain | Maria Manuela of Portugal (1527-1545) Mary I of England (1516-1558) Elizabeth of Angoulême (1545-1568) Maria Manuela of Portugal (1527-1545) Mary I of England (1516-1558) Elizabeth of Angoulême (1545-1568) Anna of Austria (1549-1580) |
| Maria of Spain (1528-1603) | 21 June 1528 Madrid, Spain | 26 February 1603 Madrid, Spain | Maximilian II, Holy Roman Emperor (1527-1576) |
| Juana of Spain (1537-1573) | 24 June 1537 | 7 September 1573 | João of Portugal (1537-1554) |
Footnotes (including sources)
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