James Mullikin III was born 13 August 1681 in Prince Frederick, Maryland, United States to James Gunnell Mullikin (1661-1718) and Jane Prather (1662-1710) and died 25 April 1740 Annapolis, Maryland, United States of unspecified causes.
Children
| Name | Birth | Death | Joined with |
| James Mulliken (1708-1749) | 5 March 1708 Annapolis, Maryland, United States | 25 September 1749 Annapolis, Maryland, United States | Mary Pottinger (1710-1776) |
Siblings
| Name | Birth | Death | Joined with |
| James Mullikin (1681-1740) | 13 August 1681 Prince Frederick, Maryland, United States | 25 April 1740 Annapolis, Maryland, United States | Charity Belt (1686-1768) |