John Higginson III was born 20 August 1675 in Salem, Essex County, Massachusetts to John Higginson (1646-1719) and Sarah Savage (1653-1713) and died 26 April 1718 Salem, Essex County, Massachusetts of unspecified causes. He married Hannah Gardner (1676-1713) 11 September 1695 in Lynn, Essex County, Massachusetts. He married Margaret Sewall (1687-1736) 11 November 1714 in Newbury, Essex County, Massachusetts.
Children
| Name | Birth | Death | Joined with |
| Elisabeth Higginson (1676-1713) | |||
| John Higginson (1697-1744) | 10 January 1697 Salem, Essex County, Massachusetts | 15 July 1744 Salem, Essex County, Massachusetts | Ruth Boardman (1698-1727) Esther Cabot (1706-1739) |
| Samuel Higginson (1700-1702) | |||
| Sarah Higginson (1702-1746) | 13 February 1702 Salem, Essex County, Massachusetts, United States | 14 June 1746 Salem, Essex County, Massachusetts, United States | John Cabot (1704-1749) |
| Francis Higginson (1705-1705) | |||
| Henry Higginson (1707-1708) | |||
| Name | Birth | Death | Joined with |
| Stephan Higginson (1716-1761) | 31 July 1716 Salem, Essex County, Massachusetts, United States | 12 October 1761 Newburyport, Essex County, Massachusetts, United States | Elizabeth Cabot (1715-1797) |
| Nathaniel Higginson (1718-1719) | |||
Siblings
| Name | Birth | Death | Joined with |
| Mary Higginson (1673-1739) | |||
| John Higginson (1675-1718) | 20 August 1675 Salem, Essex County, Massachusetts | 26 April 1718 Salem, Essex County, Massachusetts | Hannah Gardner (1676-1713) Margaret Sewall (1687-1736) |
| Thomas Higginson (1677-1678) | |||
| Joseph Higginson (1680-1761) | |||
| Nathaniel Higginson (1680-1720) | |||
| Sarah Higginson (1682-1750) | |||
| Elizabeth Higginson (1684-1734) | |||
| Margaret Higginson (1686-1688) | |||