John Lewis was born circa 1666 in Barnstable, Barnstable County, Massachusetts to Edward Lewis (1633-1703) and Hannah Cobb (1639-) and died 8 March 1738 Barnstable, Barnstable County, Massachusetts of unspecified causes. He married Elizabeth Huckins (1671-1741) 4 June 1695 in Hardwick, Worcester County, Massachusetts.
Children
| Name | Birth | Death | Joined with |
| Edward Lewis (1697-1747) | |||
| Thankful Lewis (1698-) | |||
| John Lewis (1700-1737) | |||
| Elizabeth Lewis (1701-1769) | |||
| James Lewis (1703-1730) | |||
| Gersham Lewis (1704-1766) | 30 December 1704 Barnstable, Barnstable County, Massachusetts | 18 October 1766 Litchfield, Litchfield County, Connecticut | Mary Maltby (1708-1793) |
| Shubael Lewis (1705-1766) | |||
| John Lewis (1706-) | |||
Siblings