John Prettyman was born 24 June 1653 in Accomac, Virginia, United States to John Prettyman (1609-1688) and Mary Kirby (1633-1688) and died 25 March 1724 Lewes, Delaware, United States of unspecified causes.
Children
| Name | Birth | Death | Joined with |
| Thomas Prettyman (1687-1719) | 26 March 1687 Chincoteague, Virginia, United States | 19 July 1719 Indian River Hundred, Delaware, United States | Comfort Burton (1689-1762) |
Siblings
| Name | Birth | Death | Joined with |
| John Prettyman (1653-1724) | 24 June 1653 Accomac, Virginia, United States | 25 March 1724 Lewes, Delaware, United States | Mary Mariner (1649-1690) |