Mary Asheton Southworth was born circa 1536 in Offerton, Derbyshire, England to Richard Asheton (c1496-1549) and Anne Bellingham (c1495-) and died 3 November 1595 Samesbury Hall, Samlesbury, Lancashire, England of unspecified causes. She married John Southworth (1526-1595) 1546 JL in England.
Children
| Name | Birth | Death | Joined with |
| Thomas Southworth (1548-1616) | 1548 Samlesbury, Lancashire, England | 30 November 1616 Grays Inn, London, Middlesex, England | Rosamond Lister (1554-1582) Constance Unknown Southworth (c1550-) |
| Mary Southworth (1552-) | |||
| Anne Southworth (1554-) | |||
| Margaret Southworth (1555-) | |||
| Richard Southworth (1556-) | |||
| Gilbert Southworth (1562-) | |||
| John Southworth (1563-) | |||
| Leonard Southworth (1565-) | |||
Siblings