Mary Lowell Oliver Appleton was born 7 June 1640 in Newbury, Essex County, Massachusetts to John Oliver (1600-1642) and Joanna Lowell (1609-1677) and died 15 February 1692 Ipswich, Essex County, Massachusetts of unspecified causes. She married Samuel Appleton (1624-1696) 8 December 1656 in Ipswich, Essex County, Massachusetts.
Children
| Name | Birth | Death | Joined with |
| John Appleton (1660-1724) | |||
| Isaac Appleton (1664-1747) | 1664 Ipswich, Essex County, Massachusetts | 22 May 1747 Ipswich, Essex County, Massachusetts | Priscilla Baker (1674-1731) |
| Joseph Appleton (1674-1689) | |||
| Oliver Appleton (1676-1676) | |||
| Mary Appleton (1676-1676) | |||
| Oliver Appleton (1677-1759) | 3 June 1677 Ipswich, Essex County, Massachusetts | 9 January 1759 Ipswich, Essex County, Massachusetts | Sarah Perkins (1684-1769) |
| Mary Appleton (1679-1689) | |||
Siblings