Mathilde von Hessen was born 1 July 1473 in Blankenstein, Germany to Heinrich III. von Hessen-Marburg (1440-1483) and Anna von Katzenelnbogen (1443-1494) and died 19 February 1505 Cologne, Germany of unspecified causes. She married Johann II. von Kleve (1458-1521) 3 November 1489 JL .
Children
| Name | Birth | Death | Joined with |
| Johann III. von Kleve (1490-1539) | 10 November 1490 | 6 February 1539 | Maria von Jülich (1491-1543) |
| Anna von Kleve (1495-1567) | 1495 | 1567 | Philipp III. von Waldeck-Eisenberg (1486-1539) |
| Adolf von Kleve (1498-1525) | |||