Moses Simmons was born 1681 in Duxbury, Plymouth County, Massachusetts to John Simmons (1647-1715) and Mercy Pabodie (1649-1728) and died 21 June 1761 Duxbury, Plymouth County, Massachusetts of unspecified causes. He married Rachel Sampson (1690-1761) 26 March 1718 in Duxbury, Plymouth County, Massachusetts.
Children
| Name | Birth | Death | Joined with |
| Mercy Simmons (1720-1788) | |||
| Ichabod Simmons (1722-1798) | |||
| Lydia Simmons (1724-) | |||
| Noah Simmons (1728-1737) | |||
| Deborah Simmons (1732-1784) | |||
| William Simmons (1736-1831) | |||
| Anna Simmons (1739-) | |||
| Dorithy Simmons (1741-) | |||
| Lemuel Simmons (1743-) | |||
| Abigail Simmons (1745-) | |||
Siblings
| Name | Birth | Death | Joined with |
| John Simmons (1671-1739) | |||
| William Simmons (1672-1765) | 24 September 1672 Duxbury, Plymouth County, Massachusetts | 31 August 1765 Little Compton, Newport County, Rhode Island | Abigail Church (1680-1720) |
| Ichabod Simmons (1674-) | |||
| Isaac Simmons (1674-1767) | |||
| Martha Simmons (1677-1750) | 17 November 1677 Duxbury, Plymouth County, Massachusetts, United States | 7 July 1750 Pembroke, Plymouth County, Massachusetts, United States | Ebenezer Delano (1675-1706) |
| Benjamin Simmons (1680-1749) | February 1680 Duxbury, Plymouth County, Massachusetts | 15 January 1749 Duxbury, Plymouth County, Massachusetts | Laura Sampson (1688-1715) Priscilla Delano (1686-1747) |
| Moses Simmons (1681-1761) | 1681 Duxbury, Plymouth County, Massachusetts | 21 June 1761 Duxbury, Plymouth County, Massachusetts | Rachel Sampson (1690-1761) |
| Joseph Simmons (1683-1671) | |||
| Rebecca Simmons (1683-1761) | |||
| Joshua Simmons (1688-1774) | |||