Constance Hopkins was a Mayflower passenger in 1620. By 22 May 1627 she had married Nicholas Snow in Plymouth, Massachusetts and had twelve children. Her husband was a passenger on the ship Anne in 1623 and died on 15 November 1676. Both Constance and Nicholas were buried in Cove Burying Ground Eastham, where she has an extant memorial.
NOTE: From The American Genealogist XIV:229, the theory is posed that he was the Nicholas Snow, son of Nicholas Snow (and Elizabeth (Rowles) Snow), baptized on Jan 25,1599/1600 in St.Leonards's Shoreditch, London. However, an article in the Spring 2013 Mayflower Descendant indicates that this child was buried three days later. So the birth/baptism, and the parents, of the Nicholas Snow who married Constance Hopkins are still not known with certainty. [this note copied from the Find-A-Grave entry]