Prudence Penniman Bigelow was born circa 1772 in Braintree, Norfolk County, Massachusetts, United States to William Penniman (1731-1813) and Sarah Wilde (1728-1804) and died circa 1806 of unspecified causes. She married Ezekiel Knolton Bigelow (1772-1845) 1793 in New Hampshire, United States.
Children
| Name | Birth | Death | Joined with |
| Prudence Bigelow (1796-) | |||
| Sally Bigelow (1797-1813) | |||
| Louisa Bigelow (1801-1843) | |||
| Jabez Bigelow (1803-1885) | September 1803 Springfield, Windsor County, Vermont | 23 July 1885 Quincy, Norfolk County, Massachusetts | Eliza D. Greene (1811-1892) |
| Loring Bigelow (1806-1889) | |||
Siblings