Rachel Cavendish was born 7 June 1727 to William Cavendish, 3rd Duke of Devonshire (1698-1755) and Catherine Hoskins (c1700-1777) and died 7 May 1805 London, England, United Kingdom of unspecified causes. She married Horatio Walpole, 1st Earl of Orford (1723-1809) 12 May 1748 .
|Offspring of Horatio Walpole, 1st Earl of Orford and Rachel Cavendish (1727-1805)|
|Horatio Walpole, 2nd Earl of Orford (1752-1822)||June 1752||15 June 1822||Sophia Churchill (c1745-1797) Sophia Churchill (c1745-1797) Catherine Tunstall (-1807)|
|Mary Walpole (c1757-)|
|George Walpole (1758-1835)|