Samuel Harwell Jr. was born 9 August 1716 in Brunswick, Virginia, United States to Samuel Harwell (1680-1767) and Mary Coleman (1678-1767) and died 9 November 1793 Lincolnton, North Carolina, United States of unspecified causes.
Children
| Name | Birth | Death | Joined with |
| Samuel Harrell (1745-1811) | 15 March 1745 Bedford, Virginia, United States | 13 February 1811 | Mary Wilson (1741-1819) |
| Raleigh Harwell (1762-1836) | 27 May 1762 Lawrenceville, Virginia, United States | 7 August 1836 Pulaski, Tennessee, United States | Sarah Featherstone (1773-1859) |
Siblings
| Name | Birth | Death | Joined with |
| Samuel Harwell (1716-1793) | 9 August 1716 Brunswick, Virginia, United States | 9 November 1793 Lincolnton, North Carolina, United States | Abigail Anne Jackson (1712-1765) |