Sarah Hosmer Howe was born circa 1658 in Massachusetts to James Hosmer (1637-1676) and Sarah White (1641-1685) and died 1724 Middlesex County, Massachusetts of unspecified causes. She married Thomas Howe (1656-1733) 8 June 1681 in Massachusetts.
Children
| Name | Birth | Death | Joined with |
| Tabitha Howe (1684-) | |||
| James Howe (1685-1734) | |||
| Jonathan Howe (1687-1738) | 23 April 1687 Middlesex County, Massachusetts | 22 June 1738 Middlesex County, Massachusetts | Lydia Brigham (1691-1757) |
| Prudence Howe (1689-1724) | |||
| Thomas Howe (1692-1777) | 16 June 1692 Marlborough, Middlesex County, Massachusetts | 2 April 1777 Marlborough, Middlesex County, Massachusetts | Rebecca Perkins (1692-1774) |
| Sara Howe (1697-1719) | |||
Siblings