Susan Harriet Catherine Hamilton was born 9 June 1814 in Hamilton Palace, Hamilton, Lanarkshire, Scotland, United Kingdom to Alexander Douglas-Hamilton, 10th Duke of Hamilton (1767-1852) and Susan Euphemia Beckford (1786-1859) and died 28 November 1889 Cuckfield, West Sussex, England, United Kingdom of unspecified causes. She married Henry Pelham Pelham-Clinton, 5th Duke of Newcastle (1811-1864) 27 November 1832 in Hamilton Palace, Hamilton, Lanarkshire, Scotland, United Kingdom. She married Jean Alexis Opdebeeck (bef1860-) 2 January 1860 in Naples, Campania, Italy.
|Offspring of Susan Harriet Catherine Hamilton and Henry Pelham Pelham-Clinton, 5th Duke of Newcastle (1811-1864)|
|Henry Pelham Alexander Pelham-Clinton, 6th Duke of Newcastle (1834-1879)|
|Edward William Pelham-Clinton (1836-1907)|
|Susan Charlotte Catherine Pelham-Clinton (1839-1875)||7 April 1839 London, Greater London, England, United Kingdom||6 September 1875||Adolphus Frederick Charles William Vane-Tempest (1825-1864)|
|Arthur Pelham-Clinton (1840-1870)|
|Offspring of Susan Harriet Catherine Hamilton and Horatio William Walpole, 4th Earl of Orford (1813-1894)|
|Horatio Walpole (1849-)|