Thomas Brigham was born 22 February 1695 in Marlborough, Middlesex County, Massachusetts to Nathan Brigham (1671-1747) and Elizabeth Maynard (1664-1733) and died 25 November 1765 Marlborough, Middlesex County, Massachusetts of unspecified causes. He married Sarah Stratton (1695-1775) 25 January 1720 in Marlborough, Middlesex County, Massachusetts.
Children
| Name | Birth | Death | Joined with |
| Adoniram Brigham (1720-) | |||
| Lydia Brigham (1721-1748) | |||
| Ezecial Brigham (1723-1788) | |||
| Elisha Brigham (1726-1781) | |||
| Ithamar Brigham (1728-1768) | |||
| Paul Brigham (1732-1777) | 1732 Marlborough, Middlesex County, Massachusetts | 4 June 1777 Marlborough, Middlesex County, Massachusetts | Elizabeth Rice (1729-1785) |
| Thomas Brigham (1734-1740) | |||
| Ephraim Brigham (1739-1740) | |||
| Abner Brigham (1741-1746) | |||
Siblings
| Name | Birth | Death | Joined with |
| Nathan Brigham (1693-1784) | 28 November 1693 Marlborough, Middlesex County, Massachusetts, United States | 15 September 1784 Southborough, Worcester County, Massachusetts, United States | Dinah Rice (1693-1726) Hephzibah Ward (c1695-1748) Martha Gleason (c1700-) |
| Thomas Brigham (1695-1765) | 22 February 1695 Marlborough, Middlesex County, Massachusetts | 25 November 1765 Marlborough, Middlesex County, Massachusetts | Sarah Stratton (1695-1775) |
| Tabitha Brigham (1698-1731) | |||
| Elizabeth Brigham (1700-1757) | |||
| Sarah Brigham (1701-1757) | |||
| Ziporah Brigham (1704-1790) | 14 September 1704 Marlborough, Middlesex County, Massachusetts | 2 May 1790 Marlborough, Middlesex County, Massachusetts | John Warren (1701-1783) |
| Hannah Brigham (1706-1781) | 9 March 1706 Marlborough, Middlesex County, Massachusetts | March 1781 Marlborough, Middlesex County, Massachusetts | Jabez Rice (1702-1738) |
| Ephraim Brigham (1707-1771) | |||