Uriah Brigham, Sr. was born 10 September 1727 in Marlborough, Middlesex County, Massachusetts to Samuel Brigham (1689-1771) and Abigail Moore (1696-1731) and died 23 October 1782 Marlborough, Middlesex County, Massachusetts of unspecified causes. He married Sarah Breck Gott (1729-1815) 12 July 1750 in Massachusetts.
Biography
Revolutionary War
Veteran of the American Revolutionary War, he is listed in Marlborough 1775 Minuteman Roster of militia men that responded to the Lexington alarm of 19 April 1775.
Children
| Name | Birth | Death | Joined with |
| John Gott Brigham (1750-1816) | |||
| Henry Brigham (1752-1829) | 26 October 1752 Marlborough, Middlesex County, Massachusetts | 26 January 1829 Barre, Worcester County, Massachusetts | Anna Phillips (1753-1798) |
| Sarah Brigham (1755-1799) | |||
| Uriah Brigham (1757-1820) | 11 July 1757 Marlborough, Middlesex County, Massachusetts | 16 September 1820 Bakersfield, Franklin County, Vermont | Elizabeth Fay (1767-1809) |
| Abigail Brigham (1759-1809) | |||
| Persis Brigham (1762-1841) | |||
| Edward Brigham (1764-1827) | |||
| Nathaniel Brigham (1766-1767) | |||
| Robert Brigham (1769-1770) | |||
| Anne Brigham (1773-1823) | |||
| Robert Breck Brigham (1776-1815) | |||
Siblings
| Name | Birth | Death | Joined with |
| Samuel Brigham (1717-1717) | |||
| Sybil Brigham (1718-1807) | 15 October 1718 Marlborough, Middlesex County, Massachusetts | 27 September 1807 Arhol, Worcester County, Massachusetts | Ebenezer Goddard (1714-1762) |
| Mary Brigham (1720-1748) | |||
| Abigail Brigham (1721-1755) | |||
| Samuel Brigham (1723-1756) | |||
| Phineas Brigham (1725-1786) | |||
| Uriah Brigham (1727-1782) | 10 September 1727 Marlborough, Middlesex County, Massachusetts | 23 October 1782 Marlborough, Middlesex County, Massachusetts | Sarah Breck Gott (1729-1815) |
| George Brigham (1730-1808) | 7 March 1730 Marlborough, Middlesex County, Massachusetts | 26 March 1808 Southborough, Worcester County, Massachusetts | Mary Bragg (1735-1822) |