William Clayton was born circa 1605 in Rudgwick Parish, Sussex, England and died 1658 St. Pancras Parish, Sussex, England of unspecified causes. He married Joan Smith (c1610-1644) in England.
Children
| Name | Birth | Death | Joined with |
| William Clayton (1632-1689) | 8 December 1632 Chichester, Sussex, England | 1689 Chester County, Pennsylvania, United States of America | Prudence Lanckford (c1633-) |
Siblings