William Cotton was born 18 September 1720 in Middletown, Connecticut, United States to Samuel Cotton (1676-1760) and Experience Hall (1683-1762) and died 9 June 1788 Fairfax, Virginia, United States of unspecified causes.
Children
| Name | Birth | Death | Joined with |
| Margaret Taylor Cotton (1745-1817) | 7 March 1745 Fairfax, Virginia, United States | 9 January 1817 Adairville, Kentucky, United States | Thomas Jefferson Gorham (1739-1814) |
Siblings
| Name | Birth | Death | Joined with |
| William Cotton (1720-1788) | 18 September 1720 Middletown, Connecticut, United States | 9 June 1788 Fairfax, Virginia, United States | Mary Taylor (1723-1788) |