Winthrop Sargent II was born 6 March 1727 in Gloucester, Essex County, Massachusetts, United States to Epes Sargent (1690-1762) and Esther Maccarty (1701-1743) and died 3 December 1793 Gloucester, Essex County, Massachusetts, United States of unspecified causes. He married Judith Sanders (1731-1793) 5 April 1750 in Gloucester, Essex County, Massachusetts, United States.
Children
| Name | Birth | Death | Joined with |
| Judith Sargent (1751-1820) | |||
| Winthrop Sargent (1753-1820) | 1 May 1753 Gloucester, Essex County, Massachusetts, North America | 3 January 1820 near New Orleans, United States | Rowena Tupper (1766-1790) Mary McIntosh (1764-1844) |
| Esther Sargent (1755-1811) | 1 May 1755 Gloucester, Essex County, Massachusetts, United States | 30 November 1811 Boston, Suffolk County, Massachusetts, United States | John Stevens Ellery (1748-1797) |
| Catherine Sargent (1757-1758) | |||
| Sarah Sargent (1765-1766) | |||
| FitzWilliam Sargent (1768-1822) | 14 August 1768 Roxbury, Suffolk County, Massachusetts, United States | 6 October 1822 Newton, Middlesex County, Massachusetts, United States | Anna Parsons (1769-1860) |
| Sarah Sargent (1771-1775) | |||
Footnotes (including sources)
| ‡ General |